Recent publications
Mostovenko E, Canal CG, Cho M, Sharma K, Erdely A, Campen MJ, Ottens AK. Indirect mediators of systemic health outcomes following nanoparticle inhalation exposure. Pharmacol Ther. 2022 Jan 24:108120.
Young TL, Scieszka D, Begay JG, Lucas SN, Herbert G, Zychowski K, Hunter R, Salazar R, Ottens AK, Erdely A, Gu H, Campen MJ. Aging influence on pulmonary and systemic inflammation and neural metabolomics arising from pulmonary multi-walled carbon nanotube exposure in apolipoprotein E-deficient and C57BL/6 female mice. Inhal Toxicol. 2022 Jan 17:1-15.
Mostovenko E, Dahm MM, Schubauer-Berigan MK, Eye T, Erdely A, Young TL, Campen MJ, Ottens AK. Serum peptidome: diagnostic window into pathogenic processes following occupational exposure to carbon nanomaterials. Part Fibre Toxicol. 2021 Oct 28;18(1):39.
Herbert G, Lucas S, McVeigh C, Bolt A, Bleske B, Canal CG, Mostovenko E, Ottens AK, Gu H, Campen MJ, Noor S. Neuroinflammatory and neurometabolomic consequences from inhaled wildfire smoke-derived particulate matter in the Western United States. Toxicol Sci. 2021 Dec 4:kfab147.
Young TL, Mostovenko E, Denson JL, Begay JG, Lucas SN, Herbert G, Zychowski K, Hunter R, Salazar R, Wang T, Fraser K, Erdely A, Ottens AK, Campen MJ. Pulmonary delivery of the broad-spectrum matrix metalloproteinase inhibitor marimastat diminishes multiwalled carbon nanotube-induced circulating bioactivity without reducing pulmonary inflammation. Part Fibre Toxicol. 2021 Sep 8;18(1):34.
Mostovenko E, Saunders S, Muldoon PP, Bishop L, Campen MJ, Erdely A, Ottens AK. Carbon Nanotube Exposure Triggers a Cerebral Peptidomic Response: Barrier Compromise, Neuroinflammation, and a Hyperexcited State. Toxicol. Sci. 2021, 182(1):107-119.
Patel PD, Stafflinger JE, Marwitz JH, Niemeier JP, Ottens AK. Secreted Peptides for Diagnostic Trajectory Assessments in Brain Injury Rehabilitation. Neurorehabil. Neural Repair. 2021, 35(2):169-184.
Garcia M, Salazar R, Wilson T, Lucas S, Herbert G, Young T, Begay J, Denson JL, Zychowski K, Ashley R, Byrum S, Mackintosh S, Bleske BE, Ottens AK, Campen MJ. Early Gestational Exposure to Inhaled Ozone Impairs Maternal Uterine Artery and Cardia Function. Toxicol. Sci. 2021, 179(1):121-134.
Lizhnyak PN, Muldoon PP, Pilaka PP, Povlishock JT, Ottens AK. Traumatic Brain Injury Temporal Proteome Guides KCC2-targeted Therapy. J. Neurotrauma. 2019, 36(22):3092-3102.
Mostovenko E, Young TL, Muldoon PP, Bishop L, Canal CG, Vucetic A, Zeidler-Erdely PC, Erdely A, Campen MJ, Ottens AK. Nanoparticle Exposure Driven Circulating Bioactive Peptidome Causes Systemic Inflammation and Vascular Dysfunction. 2019, 16:20.
Lewis LSC, Muldoon PP, Pilaka PP, Ottens AK. Frontal Cortex Proteome Perturbation after Juvenile Rat Secondhand Smoke Exposure. Proteomics. 2018, 18(24):e1800268.
Aragon MJ, Topper L, Tyler CR, Sanchez B, Zychowski K, Young T, Herbert G, Hall P, Erdely A, Eye T, Bishop L, Saunders SA, Muldoon PP, Ottens AK, Campen MJ. Serum-Borne Bioactivity Caused by Pulmonary Multiwalled Carbon Nanotubes Induces Neuroinflammation via Blood-Brain Barrier Impairment. Proc. Nat. Acad. Sci. 2017, 114(10):1968-1976.
Ottens AK. Isotope dilution analysis of myelin basic protein degradation after brain injury. Neuromethods. 2016, Jul 9(114):221-242.
Aragon M, Erdely A, Bishop L, Salmen R, Weaver J, Liu J, Hall P, Eye T, Kodali V, Zeidler-Erdely P, Stafflinger JE, Ottens AK, Campen MJ. MMP-9-Dependent Serum-Borne Bioactivity Caused by Multiwalled Carbon Nanotube Exposure Induces Vascular Dysfunction via the CD36 Scavenger Receptor. Tox. Sci. 2016, 150(2):488-498.
Mumaw CL, Levesque S, McGraw C, Robertson S, Lucas S, Stafflinger JE, Campen MJ, Hall P, Norenberg JP, Anderson T, Lund AK, McDonald JD, Ottens AK, Block ML. Microglial priming through the lung-brain axis: the role of air pollution-induced circulating factors. 2016, 30(5):1880-1891.
Lizhnyak PN, Ottens AK. Proteomics: in pursuit of effective traumatic brain injury therapeutics. Expert Rev. Proteomics. 2015, 12(1):75-82.
Lizhnyak PN, Yohannes H, Ottens AK. Neuroproteome dynamics in modeled brain injury: A systems neurobiology perspective. Frontiers in Neuroengineering. 2015, 6(27):371-378.
Ottens AK, Stafflinger JE, Griffin HE, Kunz RD, Cifu DX, Niemeier JP. Post-acute Brain Injury urinary signature: a new resource for molecular diagnostics. J Neurotrauma 2014, 31(8):782-789.
Kahlon A, Ojogun N, Ragland SA, Seidman D, Troese MJ, Ottens AK, Mastronunzio JE, Truchan HK, Walker NJ, Borjesson DL, Fikrig E, Carlyon JA. Anaplasma phagocytophilum Asp14 is an invasin that interacts with mammalian host cells via its C terminus to facilitate infection. Infect. Immun. 2013, 81:65-79.
Cortes DF, Landis MK, Ottens AK. High-capacity peptide-centric platform to decode the proteomic response to brain injury. Electrophoresis. 2012, 33:3712-3719.
Fuller BF, Cortes DF, Landis MK, Yohannes H, Griffin HE, Stafflinger JE, Bowers MS, Lewis MH, Fox MA, Ottens AK. Exposure of rats to environmental tobacco smoke during cerebellar development alters behavior and perturbs mitochondrial energetics. Environ. Health Perspect. 2012, 120:1684-1691.
Thalassinos K, Vissers JP, Tenzer S, Levin Y, Thompson JW, Daniel D, Mann D, DeLong MR, Moseley MA, America AH, Ottens AK, Cavey GS, Efstathiou G, Scrivens JH, Langridge JI, Geromanos SJ. Design and application of a data-independent precursor and product ion repository. J. Am. Soc. Mass Spectrom. 2012, 23:1808-1820.
Troese MJ, Kahlon A, Ragland SA, Ottens AK, Ojogun N, Nelson KT, Walker NJ, Borjesson DL, Carlyon JA. Proteomic analysis of Anaplasma phagocytophilum during infection of human myeloid cells identifies a protein that is pronouncedly upregulated on the infectious dense-cored cell. Infect. Immuno. 2011, 79:4696-4707.
Manley GT, Diaz-Aristia R, Brophy M, Engel D, Goodman C, Gwinn K, Veenstra TD, Ling G, Ottens AK, Tortella F, Hayes RL. Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group. Arch. Phys. Med. Rehabil. 2010, 91:1667-1672.
Ottens AK, Bustamante L, Golden EC, Yao C, Hayes RL, Wang KKW, Tortella FC, Dave JR. Neuroproteomics: A biochemical means to discriminate the extent and modality of brain injury. J. Neurotrauma 2010, 27:1837-1852.
Tanimura Y, Yang MCK, Ottens AK, Lewis MH. Development and temporal organization of repetitive behavior in an animal model. Develop. Psychobiol. 2010, 85:813-824.
Fuller BF, Gold MS, Wang KKW, Ottens AK. Effects of Environmental Tobacco Smoke on Adult Rat Brain Biochemistry. J. Mol. Neurosci. 2010, 41:165-171.
Young TL, Scieszka D, Begay JG, Lucas SN, Herbert G, Zychowski K, Hunter R, Salazar R, Ottens AK, Erdely A, Gu H, Campen MJ. Aging influence on pulmonary and systemic inflammation and neural metabolomics arising from pulmonary multi-walled carbon nanotube exposure in apolipoprotein E-deficient and C57BL/6 female mice. Inhal Toxicol. 2022 Jan 17:1-15.
Mostovenko E, Dahm MM, Schubauer-Berigan MK, Eye T, Erdely A, Young TL, Campen MJ, Ottens AK. Serum peptidome: diagnostic window into pathogenic processes following occupational exposure to carbon nanomaterials. Part Fibre Toxicol. 2021 Oct 28;18(1):39.
Herbert G, Lucas S, McVeigh C, Bolt A, Bleske B, Canal CG, Mostovenko E, Ottens AK, Gu H, Campen MJ, Noor S. Neuroinflammatory and neurometabolomic consequences from inhaled wildfire smoke-derived particulate matter in the Western United States. Toxicol Sci. 2021 Dec 4:kfab147.
Young TL, Mostovenko E, Denson JL, Begay JG, Lucas SN, Herbert G, Zychowski K, Hunter R, Salazar R, Wang T, Fraser K, Erdely A, Ottens AK, Campen MJ. Pulmonary delivery of the broad-spectrum matrix metalloproteinase inhibitor marimastat diminishes multiwalled carbon nanotube-induced circulating bioactivity without reducing pulmonary inflammation. Part Fibre Toxicol. 2021 Sep 8;18(1):34.
Mostovenko E, Saunders S, Muldoon PP, Bishop L, Campen MJ, Erdely A, Ottens AK. Carbon Nanotube Exposure Triggers a Cerebral Peptidomic Response: Barrier Compromise, Neuroinflammation, and a Hyperexcited State. Toxicol. Sci. 2021, 182(1):107-119.
Patel PD, Stafflinger JE, Marwitz JH, Niemeier JP, Ottens AK. Secreted Peptides for Diagnostic Trajectory Assessments in Brain Injury Rehabilitation. Neurorehabil. Neural Repair. 2021, 35(2):169-184.
Garcia M, Salazar R, Wilson T, Lucas S, Herbert G, Young T, Begay J, Denson JL, Zychowski K, Ashley R, Byrum S, Mackintosh S, Bleske BE, Ottens AK, Campen MJ. Early Gestational Exposure to Inhaled Ozone Impairs Maternal Uterine Artery and Cardia Function. Toxicol. Sci. 2021, 179(1):121-134.
Lizhnyak PN, Muldoon PP, Pilaka PP, Povlishock JT, Ottens AK. Traumatic Brain Injury Temporal Proteome Guides KCC2-targeted Therapy. J. Neurotrauma. 2019, 36(22):3092-3102.
Mostovenko E, Young TL, Muldoon PP, Bishop L, Canal CG, Vucetic A, Zeidler-Erdely PC, Erdely A, Campen MJ, Ottens AK. Nanoparticle Exposure Driven Circulating Bioactive Peptidome Causes Systemic Inflammation and Vascular Dysfunction. 2019, 16:20.
Lewis LSC, Muldoon PP, Pilaka PP, Ottens AK. Frontal Cortex Proteome Perturbation after Juvenile Rat Secondhand Smoke Exposure. Proteomics. 2018, 18(24):e1800268.
Aragon MJ, Topper L, Tyler CR, Sanchez B, Zychowski K, Young T, Herbert G, Hall P, Erdely A, Eye T, Bishop L, Saunders SA, Muldoon PP, Ottens AK, Campen MJ. Serum-Borne Bioactivity Caused by Pulmonary Multiwalled Carbon Nanotubes Induces Neuroinflammation via Blood-Brain Barrier Impairment. Proc. Nat. Acad. Sci. 2017, 114(10):1968-1976.
Ottens AK. Isotope dilution analysis of myelin basic protein degradation after brain injury. Neuromethods. 2016, Jul 9(114):221-242.
Aragon M, Erdely A, Bishop L, Salmen R, Weaver J, Liu J, Hall P, Eye T, Kodali V, Zeidler-Erdely P, Stafflinger JE, Ottens AK, Campen MJ. MMP-9-Dependent Serum-Borne Bioactivity Caused by Multiwalled Carbon Nanotube Exposure Induces Vascular Dysfunction via the CD36 Scavenger Receptor. Tox. Sci. 2016, 150(2):488-498.
Mumaw CL, Levesque S, McGraw C, Robertson S, Lucas S, Stafflinger JE, Campen MJ, Hall P, Norenberg JP, Anderson T, Lund AK, McDonald JD, Ottens AK, Block ML. Microglial priming through the lung-brain axis: the role of air pollution-induced circulating factors. 2016, 30(5):1880-1891.
Lizhnyak PN, Ottens AK. Proteomics: in pursuit of effective traumatic brain injury therapeutics. Expert Rev. Proteomics. 2015, 12(1):75-82.
Lizhnyak PN, Yohannes H, Ottens AK. Neuroproteome dynamics in modeled brain injury: A systems neurobiology perspective. Frontiers in Neuroengineering. 2015, 6(27):371-378.
Ottens AK, Stafflinger JE, Griffin HE, Kunz RD, Cifu DX, Niemeier JP. Post-acute Brain Injury urinary signature: a new resource for molecular diagnostics. J Neurotrauma 2014, 31(8):782-789.
Kahlon A, Ojogun N, Ragland SA, Seidman D, Troese MJ, Ottens AK, Mastronunzio JE, Truchan HK, Walker NJ, Borjesson DL, Fikrig E, Carlyon JA. Anaplasma phagocytophilum Asp14 is an invasin that interacts with mammalian host cells via its C terminus to facilitate infection. Infect. Immun. 2013, 81:65-79.
Cortes DF, Landis MK, Ottens AK. High-capacity peptide-centric platform to decode the proteomic response to brain injury. Electrophoresis. 2012, 33:3712-3719.
Fuller BF, Cortes DF, Landis MK, Yohannes H, Griffin HE, Stafflinger JE, Bowers MS, Lewis MH, Fox MA, Ottens AK. Exposure of rats to environmental tobacco smoke during cerebellar development alters behavior and perturbs mitochondrial energetics. Environ. Health Perspect. 2012, 120:1684-1691.
Thalassinos K, Vissers JP, Tenzer S, Levin Y, Thompson JW, Daniel D, Mann D, DeLong MR, Moseley MA, America AH, Ottens AK, Cavey GS, Efstathiou G, Scrivens JH, Langridge JI, Geromanos SJ. Design and application of a data-independent precursor and product ion repository. J. Am. Soc. Mass Spectrom. 2012, 23:1808-1820.
Troese MJ, Kahlon A, Ragland SA, Ottens AK, Ojogun N, Nelson KT, Walker NJ, Borjesson DL, Carlyon JA. Proteomic analysis of Anaplasma phagocytophilum during infection of human myeloid cells identifies a protein that is pronouncedly upregulated on the infectious dense-cored cell. Infect. Immuno. 2011, 79:4696-4707.
Manley GT, Diaz-Aristia R, Brophy M, Engel D, Goodman C, Gwinn K, Veenstra TD, Ling G, Ottens AK, Tortella F, Hayes RL. Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group. Arch. Phys. Med. Rehabil. 2010, 91:1667-1672.
Ottens AK, Bustamante L, Golden EC, Yao C, Hayes RL, Wang KKW, Tortella FC, Dave JR. Neuroproteomics: A biochemical means to discriminate the extent and modality of brain injury. J. Neurotrauma 2010, 27:1837-1852.
Tanimura Y, Yang MCK, Ottens AK, Lewis MH. Development and temporal organization of repetitive behavior in an animal model. Develop. Psychobiol. 2010, 85:813-824.
Fuller BF, Gold MS, Wang KKW, Ottens AK. Effects of Environmental Tobacco Smoke on Adult Rat Brain Biochemistry. J. Mol. Neurosci. 2010, 41:165-171.